Date added: 18 Mar 2014
2011 - Best Biotechnology Product: Stelara® - Janssen
STELARA has proven innovative throughout development. STELARA was the first therapeutic monoclonal antibody approved for human use developed with transgenic mice engineered to express human antibodies (Canada 2008). The low immune response to STELARA resulted in welltolerated administrations, and less rapid drug clearance allowed therapeutic drug levels to be maintained with infrequent dosing. These features confirmed the potential advantages of this methodology and established this technology as important option for development of therapeutic antibodies.